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ANTIBACTERIAL EFFECT OF FLUORIDE AND CHLORHEXIDINE AGAINST CARIGGENIC BACTERIA IN CHILDREN WITH REMOVABLE ORTHODONTIC APPLIANCES

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Abstract

°á·Ð
ÀúÀÚµéÀº ¿ì½Ä¼¼±Õ¿¡ ´ëÇÑ ºÒÈ­¹°°ú chlorhexidineÀÇ Ç×±ÕÀÛ¿ëÀ» °üÂûÇϱâ À§ÇØ Àü³²´ëÇÐ
±³º´¿ø ¼Ò¾ÆÄ¡°ú¿¡¼­ °¡Ã¶¼º ±³Á¤ÀåÄ¡·Î 6°³¿ù ÀÌ»ó Ä¡·áÁßÀÎ 7¡­11¼¼ÀÇ ¾Æµ¿ 50¸íÀ» ´ë»ó
À¸·Î 10¸íÀ» ÇÑ ±ºÀ¸·Î ÇÏ¿© ´ëÁ¶±º ¹× 4°³ÀÇ ½ÇÇ豺À¸·Î ºÐ·ùÇÏ¿´´Ù. Á¦ I±ºÀº ´ëÁ¶±ºÀ¸·Î
ÁÖ 2ȸ 2ÁÖµ¿¾È ºÒ¼Ò°¡ ÷°¡µÇÁö ¾ÊÀº pumice¿Í rubber cupÀ¸·Î Ä¡¸é¼¼¸¶ ÇÏ¿´°í, Á¦ ¥±±º
Àº 1.23% acidulated phosphate sodium fluoride¸¦ °³Àοë tray¸¦ »ç¿ëÇØ 4ºÐ°£ 1ȸ ±¹¼Òµµ
Æ÷ÇÏ¿´´Ù. Á¦¥²±ºÀº amine fluoride(ElmexgelR)·Î ÁÖ 1ȸ 2ÁÖµ¿¾È ÀÕ¼ÖÁúÇÏ¿´
°í, Á¦¥³±ºÀº ¥±±º°ú ¥²±ºÀÇ ¹æ¹ýÀ» º´¿ëÇßÀ¸¸ç, Á¦V±ºÀº 0.1% chlorhexidine digluconate
¾çÄ¡ ¾×À¸·Î 1ȸ¿¡ 15m1¾¿ 30Ãʵ¿¾È 2ÁÖ°£ ¸ÅÀÏ ¾Æħ Àú³áÀ¸·Î ¾çÄ¡ÇÏ¿´´Ù. ºÒÈ­¹°°ú
chlorhexidine óġ Àü°ú óġ 1, 3, 5ÁÖ ÈÄ ¿¬±¸´ë»óÀÇ Å¸¾×À» ¸ê±ÕµÈ ¿ë±â¿¡ äÃëÇÏ¿© Ÿ¾×
³» Streptocorccus mutans¿Í lactobacillus¸¦ °¢°¢ Mitis-Salivarius-Bacitracin(MSB) ¹èÁö¿Í
Rogosa SL ¹èÁö¿¡¼­ ¹è¾çÇÏ¿© °üÂûÇÑ ¹Ù ´ÙÀ½°ú °°Àº °á°ú¸¦ ¾ò¾ú´Ù.
1. Ÿ¾×³» Streptocorccus mutansÀÇ ¼ö´Â óġ Àü 1.13¡¿106 CFU/ml,
lactobacillus´Â 6.43¡¿105 CFU/mlÀ̾ú´Ù.
2. Ÿ¾×³» Streptocorccus mutans´Â óġ 1ÁÖ ÈÄ ¥±±º¿¡¼­ 6.40¡¿105, ¥²±º
¿¡¼­ 5.71¡¿105, V±º¿¡¼­ 1.16¡¿105 CFU/ml·Î óġ Àü°ú ´ëÁ¶
±º¿¡ ºñÇØ À¯ÀÇÇÑ °¨¼Ò°¡ ÀÖ¾ú´Ù(p¡»0.05).
3. Streptocorccus mutansÀÇ ¼ö´Â óġ 5ÁÖ ÈÄ °ÅÀÇ ¿ø»óÀ¸·Î ȸº¹µÇ¾ú´Ù.
4. Lactobaciilus´Â ¸ðµç ±º¿¡¼­ óġ ÀüÈÄ À¯ÀÇÇÑ Â÷À̸¦ º¸ÀÌÁö ¾Ê¾Ò´Ù.
ÀÌ»óÀÇ ¿¬±¸°á°ú·Î ¹Ì·ïº¸¾Æ Ä¡¾Æ¿ì½ÄÁõÀÇ ¹ß»ýÀ²ÀÌ ³ôÀº °¡Ã¶¼º ±³Á¤ÀåÄ¡ ÀåÂøȯÀÚ¿¡¼­
Áö¼ÓÀûÀÎ chlorhexidineÀ̳ª ºÒÈ­¹°ÀÇ »ç¿ëÀ¸·Î Streptocorccus mutans¿¡ ÀÇÇÑ Ä¡¾Æ¿ì½ÄÁõ
À» »ó´çÈ÷ ¿¹¹æÇÒ ¼ö ÀÖÀ» °ÍÀ¸·Î »ç·áµÈ´Ù.
#ÃÊ·Ï#
The purpose of this study was to examine the antibacterial activities of fluoride and
chlorhexidine against Streptococcus mutans and lactobacillus.
All subjects had not taken antibacterial medication at least one month before
treatment. They were divided into 5 groups : Group I had been treated with placebo gel,
Group ¥± with 1.23% sodium fluoride, Group ¥² with amino fluoride, Group ¥³ with
1.23% sodium fluoride and azine fluoride, and Group V with 0.1% chlorhexidine solution.
Salivary samples were collected from 50 children who had been treated with removable
orthodontic appliances in the Department of Pedodontics, Chonnam National University
Hospital. The number of Streptococcus mutans and lactobacillus in saliva were
monitored by using the Mitis-Salivarius-Bacitracin agar plate and Rogosa SL agar plate
for 5 weeks after the treatment.
The results were as follow :
1. The mean number of salivary Streptococcus mutans and lactobacillus was 1.13¡¿
106CFU/ml, 6.43¡¿105 CFU/ml before treatment.
2. The number of salivary Streptococcus mutans were significantly reduced to 6.40¡¿
105CFU/ml in Group ¥±, 5.71¡¿105CFU/ml in Group ¥², 2.16¡¿
105CFU/ml in Group ¥´, 1.16¡¿105CFU/ml in Group V in one
week after treatment(P¡»0.05).
3. The number of Streptococcus muttons was returned to the baseline at 5th week
after treatment.
4. The number of salivary lactobacillus was not significantly changed in all groups.
These results suggest that continuous application of fluoride or chlorhexidine may
prevent dental caries in patients with removable orthodontic appliances.

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